Method of collecting data for estimating the susceptibility of diseased periodontal disease

摘要

The examined based on the detection of gene mutation ability to modulate the defensin gene promoter very closely ability to express defensins are one of the antimicrobial peptides, a method for estimating the incidence sensitivity of periodontal disease in the future. Determining the suitability of the PCR amplification and / or sequence homology with a nucleic acid sequence comprising a DNA of the defensin gene promoter from that present in a sample obtained from and gum tissue of the subject, the mutation sequence portion of the promoter region , thereby making it possible to collect the data estimation by determining the detection of gene mutation, the mutation site of the gene.