Medicinal uses of histone deacetylase inhibitors and methods for evaluating their antitumor effects

摘要

A therapeutic agent for prostate cancer and a therapeutic agent for malignant lymphoma comprising FK228 or a salt thereof as an active ingredient, and at least a step of treating a test cell with a histone deacetylase inhibitor, and the test cell before and after the treatment of the inhibitor A method for evaluating the antitumor effect of a histone deacetylase inhibitor, comprising measuring a change in expression of a specific gene in, and comparing the expression levels of the two.