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Use of eNOS transcription enhancers in the cell therapy of ischemic heart diseases
Use of eNOS transcription enhancers in the cell therapy of ischemic heart diseases
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机译:eNOS转录增强子在缺血性心脏病细胞治疗中的应用
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摘要
The present invention relates to the use of compounds which enhance the transcription of endothelial nitric oxide synthase (eNOS) for treating stem and progenitor cells in the cell therapy of patients with ischemic heart diseases such as coronary heart disease or ischemic cardiomyopathy. Treatment of such cells which are isolated from bone marrow, for example, with an eNOS transcription enhancer prior to their administration improves their functional activity and ameliorates neovascularization of the heart and cardiac regeneration.
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