embedded imagewherein R1, R2, R3, R4, R5 and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases."/> Imidazo-fused oxazolo4,5-betapyridine and imidazo-fused thiazolo4,5-betapyridine based tricyclic compounds and pharmaceutical compositions comprising same
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Imidazo-fused oxazolo4,5-betapyridine and imidazo-fused thiazolo4,5-betapyridine based tricyclic compounds and pharmaceutical compositions comprising same

机译:基于咪唑并稠合的恶唑并[4,5-β]吡啶和基于咪唑并稠合的噻唑并[4,5-β]吡啶的三环化合物以及包含它们的药物组合物

摘要

The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I), embedded imagewherein R1, R2, R3, R4, R5 and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.
机译:本发明提供了具有式(I)的吡唑并嘌呤基的三环化合物, <图像alt =“嵌入式图像” file =“ US20050101626A1-20050512-C00001.GIF” he =“ 32.77mm” id =“ EMI-C00001” imgContent =“ chem” imgFormat =“ GIF” wi =“ 57.83mm” /> 其中R 1 ,R 2 ,R 3 ,R 4 ,R 5 和R 6 如本文所述。本发明进一步提供了包含此类化合物的药物组合物,以及此类化​​合物在治疗炎性和免疫性疾病中的用途。

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