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Dosing form for a polymer support, use of said dosing form in organic chemical synthesis and method for production of said dosing form
Dosing form for a polymer support, use of said dosing form in organic chemical synthesis and method for production of said dosing form
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机译:用于聚合物载体的剂量形式,所述剂量形式在有机化学合成中的用途以及生产所述剂量形式的方法
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摘要
A dosing form for a polymer support for organic chemical synthesis in a solvent medium comprising a fixed weight amount of beads of a polymer containing functional groups, which polymer is insoluble in the solvent for the intended synthesis, is provided as compressed tablets of essentially equal weight and composition wherein the polymer beads are essentially intact and are released as such when the tablets are disintegrated in said solvent. Use of the dosing form is made in conventional synthesis, in parallel synthesis, in split and mix synthesis and/or combinatorial chemistry. In a method for producing the dosing form, beads of a polymer having functional gropusgroups is compressed into tablets after pre-treatment with an aprotic organic solvent. groups are compressed into tablets after pre-treatment with an aprotic organic solvent.
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