首页> 外国专利> Peptides blocking vascular endothelial growth factor(vegf)-mediated angiogenesis, polynucleotides encoding said pepetides and methods of use thereof

Peptides blocking vascular endothelial growth factor(vegf)-mediated angiogenesis, polynucleotides encoding said pepetides and methods of use thereof

机译:阻断血管内皮生长因子(vegf)介导的血管生成的肽,编码所述肽的多核苷酸及其使用方法

摘要

The present invention provides peptides which can interact with VEGF and inhibit VEGF interaction with KDR or anti-VEGF antibody thereby inhibiting VEGF mediated angiogenesis or angiogeneis related diseases, polynucleotide encoding the peptides, vectors containing the polynucleotides, pharmaceutical compositions containing the peptides, and methods of inhibiting angiogenesis with the peptides.
机译:本发明提供了可与VEGF相互作用并抑制VEGF与KDR或抗VEGF抗体的相互作用从而抑制VEGF介导的血管生成或血管生成相关疾病的肽,编码该肽的多核苷酸,包含该多核苷酸的载体,包含该肽的药物组合物和方法抑制肽的血管生成。

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