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Molecular diagnosis of atypical Mycobacterial infections

机译：非典型分枝杆菌感染的分子诊断

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摘要

The present invention provides methods for diagnosing mycobacteria other than tuberculosis (MOTT) infections in patients comprising amplifying the internal transcribed spacer sequence (ITSS) of 16S-23S rDNA of MOTT with primers that amplify MOTT but not Mycobacteria Tuberculosis (MTB). The present invention also provides a method for differentiating between MOTT and MTB infections comprising amplifying MOTT with primers that amplify MOTT but not MTB; amplifying MTB with primers that amplify MTB but not MOTT; and detecting approximately 130 base pair product indicative of MOTT and approximately 180 base pair product indicative of MTB.

机译：本发明提供了用于诊断患者中结核分枝杆菌（MOTT）感染之外的分枝杆菌的方法，包括扩增MOTT的 16 S- 23 S rDNA的内部转录间隔区序列（ITSS）用能扩增MOTT但不能扩增结核分枝杆菌（MTB）的引物。本发明还提供了一种区分MOTT和MTB感染的方法，该方法包括用扩增MOTT但不扩增MTB的引物扩增MOTT。用能扩增MTB但不能扩增MOTT的引物扩增MTB;并检测指示MOTT的大约130个碱基对产物和指示MTB的大约180个碱基对产物。 展开▼

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公开/公告号US2005214770A1

专利类型

公开/公告日2005-09-29

原文格式PDF

申请/专利权人 KUNAPULI T. MADHUSUDHAN;
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申请/专利号US20030692905

发明设计人 KUNAPULI T. MADHUSUDHAN;
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申请日2003-10-25

分类号C12Q1/68;C12P19/34;

国家 US

入库时间 2022-08-21 22:23:21

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