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Expression vector containing urea cycle enzyme gene, transformant thereof, and use of transformant for protein over-expression
Expression vector containing urea cycle enzyme gene, transformant thereof, and use of transformant for protein over-expression
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机译:包含尿素循环酶基因的表达载体,其转化体以及该转化体在蛋白质过表达中的用途
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摘要
The present invention relates to expression vectors containing in vivo urea cycle enzyme gene; transformants thereof; and the use of transformants for protein overexpression. During the overexpression of protein, if the animal cell transformed with expression vectors of the present invention is used, amounts of ammonia accumulation within cell culture medium will decrease and cell growth rate will increase, thus, it is advantageous to be capable of obtaining desired protein in high yields.
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