Process for preparing highly pure androstane 17-beta-carboxylic acids and 17-beta-carbothioic acid fluoromethyl esters thereof

摘要

The present invention relates to an oxidation process for preparing the androstane 17-β-carboxylic acid of general formula (I) with a high purity degree by oxidative demolition of the carbon atom 21 of the compound of general formula (II) by using hydrogen peroxide in a basic environment in a polar solvent optionally in the presence of water.