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Granulin-epithelin precursor (GEP) overexpression as a target for diagnosis, prognosis and treatment of hepatocellular carcinoma (HCC)
Granulin-epithelin precursor (GEP) overexpression as a target for diagnosis, prognosis and treatment of hepatocellular carcinoma (HCC)
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机译:颗粒蛋白-上皮素前体(GEP)的过量表达可作为诊断,预后和治疗肝细胞癌(HCC)的目标
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摘要
This invention further provides methods for determining whether an agent causes a reduction in the activity of a Granulin-Epithelin Precursor (GEP) protein in a cell. This invention also provides methods for reducing the expression of Granulin-Epithelin Precursor (GEP) protein in a cell. This invention also provides methods for determining whether a subject is afflicted with Hepatocellular carcinoma (HCC). This invention provides methods for determining whether a subject is afflicted with Hepatocellular carcinoma (HCC) This invention further provides a method for treating a subject afflicted with Hepatocellular carcinoma (HCC) comprising administering to the subject a therapeutically effective amount of an agent which specifically interferes with the expression of the Granulin-Epithelin Precursor (GEP) protein in the tumor cells of the subject.
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