首页>
外国专利>
Engineered Fab' fragment anti-tumor necrosis factor alpha in combination with disease modifying anti-rheumatic drugs
Engineered Fab' fragment anti-tumor necrosis factor alpha in combination with disease modifying anti-rheumatic drugs
展开▼
机译:工程化Fab'片段抗肿瘤坏死因子α结合疾病改良抗风湿药
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides a combination therapeutic composition useful in modulating, treating and/or preventing inflammatory diseases. The therapeutic composition includes antibody Fab′ fragment CDP870 that is specific for antigenic determinants of tumor necrosis factor alpha and at least one Disease Modifying Anti-Rheumatic Disease drug such as methotrexate or sulfasalazine. The therapeutic composition can be administered to either a human or animal subject in single or multiple doses over time in the treatment of rheumatoid arthritis, Crohn's Disease or any other inflammatory disease.
展开▼