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Citrullimycines, a process for their production and their use as pharmaceuticals
Citrullimycines, a process for their production and their use as pharmaceuticals
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机译:柑桔霉素,其生产过程及其作为药物的用途
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摘要
The present invention relates to novel active compounds named Citrullimycines, which are obtainable by cultivation of Streptomyces sp. ST 101396 (DSM 13309), and to their pharmaceutically acceptable salts and derivatives. The present invention further relates to a process for the production of the Citrullimycines, to the microorganism Streptomycetes sp. ST 101396 (DSM 13309), to the use of the Citrullimycines and their pharmaceutically acceptable salts and derivatives as pharmaceuticals, for example as inhibitors of the neurotensin receptor, and to pharmaceutical compositions comprising Citrullimycines or a pharmaceutically acceptable salt or derivative thereof.
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机译:本发明涉及新的活性化合物,名为瓜特罗霉素,可通过培养链霉菌 i> sp获得。 ST 101396(DSM 13309)及其药学上可接受的盐和衍生物。本发明还涉及生产瓜氨酸霉素的方法,涉及微生物链霉菌 I> sp。 ST 101396(DSM 13309),涉及柑桔霉素及其药学上可接受的盐和衍生物作为药物的用途,例如作为神经降压素受体的抑制剂,并且涉及含有柑桔霉素或其药学上可接受的盐或衍生物的药物组合物。
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