首页> 外国专利> Mice lacking alpha 1G showing enhanced novelty-seeking and alcohol preference and therapeutic methods for mood disorders by modulating alpha 1G T-type calcium channels

Mice lacking alpha 1G showing enhanced novelty-seeking and alcohol preference and therapeutic methods for mood disorders by modulating alpha 1G T-type calcium channels

机译:缺乏α1G的小鼠通过调节α1GT型钙通道表现出更高的寻求新颖性和酒精偏好以及用于情绪障碍的治疗方法

摘要

The present invention relates to a novel use of an α1G T-type calcium channel transgenic mouse as a nervous disease model, more particularly, a novel use of a mouse deficient in α1G T-type calcium channel showing novelty-seeking and alcohol preference as a nervous disease model for human nervous related diseases such as novelty-seeking character, alcoholism, anxiety and emotion disorder by stress, etc. The α1G T-type channel transgenic mice showing novelty-seeking and alcohol preference of the present invention can be effectively used for the development of a medicine and a therapeutic method for human nervous diseases.
机译:本发明涉及一种α1GT型钙通道转基因小鼠作为神经疾病模型的新用途,更具体地说,涉及一种缺乏α1GT型钙通道的小鼠的新颖用途,该小鼠表现出寻求新颖性和对酒精的偏好。用于人类神经相关疾病的神经疾病模型,例如寻求新奇特征,酗酒,焦虑和因压力引起的情绪失调等。本发明显示出寻求新奇和嗜好酒精的α1GT型通道转基因小鼠可以有效地用于人类神经疾病的药物和治疗方法的开发。

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