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Recombinant human SM-11044-binding receptor proteins exhibiting ligand-binding activities, and their uses
Recombinant human SM-11044-binding receptor proteins exhibiting ligand-binding activities, and their uses
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机译:具有配体结合活性的重组人SM-11044结合受体蛋白及其用途
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摘要
Transformed cells designed to express a recombinant human SMBP at an elevated level to the extent that its ligand-binding activity can be measured, and cellular membrane fractions thereof; recombinant human SMBPs isolated from the transformed cells or the cellular membrane fractions thereof; a screening system for human SMBP agonists/antagonists characterized by utilizing the transformed cells, the cellular membrane fractions thereof or the isolated recombinant human SMBPs; and human SMBP agonists or antagonists obtainable by the screening system, are provided by deleting the polythymidine sequence from the base sequence of the 3-untranslated region.
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