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Species-specific PCR assay for detection of Leishmania donovani in clinical samples of kala-azar and post kala-azar dermal leishmaniasis

机译：用于检测黑热病和黑热病后皮肤利什曼病临床样品中的利什曼原虫的物种特异性PCR检测

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摘要

The present invention relates to a polymerase chain reaction (PCR) assay for the diagnosis of leishmaniasis using specific oligonucleotide primers for the identification of Leishmania donovani parasites in clinical samples.

机译：本发明涉及用于诊断利什曼病的聚合酶链反应（PCR）测定法，该方法使用特定的寡核苷酸引物鉴定临床样品中的利什曼原虫。 展开▼

著录项

公开/公告号US6855522B2

专利类型

公开/公告日2005-02-15

原文格式PDF

申请/专利权人 POONAM SALOTRA;GANNAVARAN SREENIVAS;GREGORY P. POGUE;HIRALAL NAKHASI;
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申请/专利号US20020086184

发明设计人 POONAM SALOTRA;GANNAVARAN SREENIVAS;GREGORY P. POGUE;HIRALAL NAKHASI;
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申请日2002-02-27

分类号C12P19/34;C12Q1/68;C07H21/04;

国家 US

入库时间 2022-08-21 22:20:18

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1. 检测亲内脏利什曼原虫感染和诊断黑热病的免疫层析试条 [P] . 中国专利： CN102590508A . 2012-07-18

2. 一种基于检测循环抗原的诊断黑热病的免疫层析试条 [P] . 中国专利： CN104142400B . 2016.09.07

3. Species-specific PCR assay for detection of Leishmania donovani in clinical samples of kala-azar and post kala-azar dermal leishmaniasis [P] . 美国专利： US2003162182A1 . 2003-08-28

机译：用于检测黑热病和黑热病后皮肤利什曼病临床样品中的利什曼原虫的物种特异性PCR检测

4. A NOVEL PCR ASSAY FOR THE DETECTION OF LEISHMANIA DONOVANI ORGANISM [P] . IN2005DE03362A . 2010-04-23

机译：新型PCR检测利什曼原虫的检测方法。

5. A HYBRID CELL VACCINE AGAINST LEISHMANIASIS KALA-AZAR [P] . PT2037958E . 2012-05-14

机译：抗利什曼病的混合细胞疫苗[KALA-AZAR]

1. Leishmania donovani-Induced Immune Dysregulation among Sudanese Patients with Visceral and Post Kala-Azar Dermal Leishmaniases: Possible Roles in Pathogenesis [J] . Elsamani Elmotwafig Mohamed Elsammani, Brima Younis Musa, Mona Elfaki Eltahir Elfaki, 传染病进展（英文） . 2020,第004期

2. Jaundice in pediatric visceral leishmaniasis (kala-azar)pa-tients [J] . AKMMamunur Rashid, MdAsrafuzzaman, Abdullah Al Mamun, 亚太热带医药杂志（英文版） . 2009,第002期

3. Immunogenicity and efficacy of recombinant 78 kDa antigen of Leishmania donovani formulated in various adjuvants against murine visceral leishmaniasis [J] . Rajeev Nagill, Tejinder Kaur, Jyoti Joshi, 亚太热带医药杂志（英文版） . 2015,第007期

4. Leishmania donovani whole cell antigen delivered with adjuvants protects against visceral leishmaniasis in vervet monkeys (Chlorocebus aethiops) [J] . Joshua Muli Mutiso, John Chege Macharia, Evans Taracha, 生物医学研究杂志（英文版） . 2012,第001期

5. Leishmania donovani whole cell antigen delivered with adjuvants protects against visceral leishmaniasis in vervet monkeys （Chlorocebus aethiops） [J] . Joshua Muli Mutiso, John Chege Macharia, Evans Taracha, 生物医学研究杂志：英文版 . 2012,第001期

6. RISK ZONE MODELLING AND EARLY WARNING SYSTEM FOR VISCERAL LEISHMANIASIS (KALA-AZAR) DISEASE IN BIHAR, INDIA USING REMOTE SENSING AND GIS [C] . A. Jeyaram, Shreekant Kesari, Anju Bajpai, Imaging a Sustainable Future . 2012

7. Characterization of the post-translational modifications of the secreted acid phosphatase of Leishmania donovani. [D] . Lippert, Duston Norman Dean. 2002

8. Development of a Species-Specific PCR Assay for Detection of Leishmania donovani in Clinical Samples from Patients with Kala-Azar and Post-Kala-Azar Dermal Leishmaniasis [O] . Poonam Salotra, G. Sreenivas, Gregory P. Pogue, 2001

9. Development of a Species-Specific PCR Assay for Detection of Leishmania donovani in Clinical Samples from Patients with Kala-Azar and Post-Kala-Azar Dermal Leishmaniasis [O] . Salotra, Poonam, Sreenivas, G., Pogue, Gregory P., 2001

10. Visceral Leishmaniasis in the Golden Hamster as a Model for Human Kala-Azar [R] . Farrell, J. P. 1988

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