2,4-Di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as antineaoplastic agents

摘要

Pyrimidine derivatives of formula (I) wherein Q₁, Q₂, G and R¹ are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.