首页> 外国专利> Selection of strains of Poultry Eimeria sporozoites through extra - intestinal

Selection of strains of Poultry Eimeria sporozoites through extra - intestinal

机译:通过肠外筛选家禽艾美球虫子孢子菌株。

摘要

A method to obtain a useful immunogenic Strain to produce a Vaccine against coccidiosis infection Cycle includes at least a First Group of donors with specific pathogen free Birds of a species of Eimeria oocytes. Then, It collects Blood Donors of these Birds, and then used to Infect a second group of Specific Pathogen Free Chickens.Oocytes were collected from the second group of Birds. These oocytes are then multiplied to complete the Cycle. Then the cycle is repeated using oocytes multiplied. After a total of approximately three cycles, an Antigen can be collected and used as a source to generate oocytes for a vaccine.Claim: (1) a Strain isolated oocytes to generate useful immunogens for Vaccination against coccidiosis. Claim (3): an effective Vaccine against coccidiosis comprising at least approximately 104 Eimeria oocytes per dose attenuated, together with a pharmaceutically acceptable Carrier. Vindication (27): Eimeria oocytes derived from acervulina, and such.Acervulina attenuated by approximately three cycles of Passage through specific pathogen free Chickens. Vindication (28): a Eimera strain that has the characteristics of the strain and immunogenic.Acervulina deposited in the European Collection of Cell Cultures under the Access Number 02010911 Claim (29) taking the vaccine: a vaccine Antigen Response Properties of a Vaccine against coccidiosis inmunogenizante containing a number of oocytes obtained from the CEP To e.Acervulina deposited in the European Collection of Cell Cultures under the Access Number 02010911
机译:一种获得有用的免疫原性菌株以生产针对球虫感染周期的疫苗的方法,该方法包括至少第一批具有特定的无病原体的艾美球虫卵母细胞的供体。然后,它收集这些鸟的献血者,然后用于感染第二组无特定病原体的鸡。从第二组鸟中收集卵母细胞。然后将这些卵母细胞繁殖以完成循环。然后使用倍数的卵母细胞重复该循环。在总共大约三个周期后,可以收集抗原并将其用作产生疫苗卵母细胞的来源。声明:(1)分离出的卵母细胞株以产生用于针对球虫病进行疫苗接种的有用免疫原。权利要求(3):一种抗球虫病的有效疫苗,每剂减毒剂量至少包含约104个艾美球虫卵母细胞,以及可药用的载体。辩护(27):源自小头孢子虫等的艾美球虫卵母细胞。小头孢菌素通过无特定病原体鸡的传代约三个周期而减毒。 Vindication(28):具有该菌株特征和免疫原性的艾美拉球菌(Eimera菌株)。根据访问号02010911在欧洲细胞培养物保藏中心保藏的小球菌(29)服用该疫苗:一种疫苗球虫病的抗原反应特性含有许多从CEP到小孢子虫的卵母细胞的致免疫原,该小卵母细胞保存在欧洲细胞培养物保藏中心,保藏号为02010911

著录项

  • 公开/公告号AR038485A1

    专利类型

  • 公开/公告日2005-01-19

    原文格式PDF

  • 申请/专利权人 WYETH;

    申请/专利号AR2003P100426

  • 发明设计人

    申请日2003-02-11

  • 分类号C12N1/10;C12N1/36;C12N3/00;A61K35/68;A61K39/012;A61P33/02;

  • 国家 AR

  • 入库时间 2022-08-21 22:18:54

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