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Use of alquilfosfocolinas in combination with antitumor drugs for the treatment of malignant and benign oncosis in human beings and Animals

机译:Alquilfosfocolinas与抗肿瘤药联合用于治疗人类和动物的恶性和良性肿瘤的用途

摘要

3. Combined with anti-tumor drugs, fluooctylsulfonylamine was used to treat benign and malignant tumors in human and animals. In connection with this connection, the ionosphere may be used in combination with one or more approved cell growth inhibitors. The preferred ionosphere is described by formula (1). 1. Characteristic 1: use hydrofluorocarbons in general equations (1) and (2), in which none is independent: n, m, P, Z is an integer from 0 to 4; X is O, s, NH; R is h,1. One to three double bonds and / or triple bonds of rectum or separator that may be saturated or unsaturated or unsaturated, and may not be replaced or replaced by one, two or more halogen, nitrogen, cyanogen, hydroxyl, alcoxi - (C1-6) in the same or different C atom;Amino, single (C1-4) or di rental (C1-4). R1, R2, R3 are independent, h, a radical tar (C1-6), preferably methyl and ethyl, a cyclopentyl (c3-7) radical,In the same or different C atom, it may not be replaced or replaced by one, two or more halogen, nitrogen, cyanogen, hydroxyl, oxygen - (C1-6),Amino, mono - (C1-4) or di - (C1-4),1. Manufacture a drug for the treatment of benign and malignant tumors before and / or during the treatment of approved antineoplastic drugs;
机译:3.氟辛基磺胺与抗肿瘤药联合用于治疗人和动物的良性和恶性肿瘤。关于这一点,电离层可以与一种或多种批准的细胞生长抑制剂结合使用。优选的电离层由式(1)描述。 1.特征1:在通式(1)和(2)中使用氢氟烃,其中没有一个是独立的:n,m,P,Z为0至4的整数; X为O,s,NH; R是h,1。直肠或分隔物的一到三个双键和/或三键可以是饱和或不饱和或不饱和的,并且不能被一个,两个或多个卤素,氮,氰,羟基,醇类取代或取代-(C1-6 )在相同或不同的C原子中;氨基,单个(C1-4)或二租赁(C1-4)。 R 1,R 2,R 3是独立的,h是焦油基(C 1-6),优选为甲基和乙基,环戊基(c 3-7)基,在相同或不同的C原子中,不能被一个或一个取代,两个或多个卤素,氮,氰,羟基,氧-(C1-6),氨基,单-(C1-4)或二-(C1-4),1。在批准的抗肿瘤药治疗之前和/或过程中,生产用于治疗良性和恶性肿瘤的药物;

著录项

  • 公开/公告号AR040717A1

    专利类型

  • 公开/公告日2005-04-20

    原文格式PDF

  • 申请/专利权人 ZENTARIS AG;

    申请/专利号AR2003P102710

  • 发明设计人

    申请日2003-07-29

  • 分类号A61K31/685;A61P35/00;

  • 国家 AR

  • 入库时间 2022-08-21 22:18:50

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