Use of a retinoid Component selected from the group consisting of active agents, retinoids retinoids, precursors of active agents and mixtures thereof for preparing a Pharmaceutical composition

摘要

Use of a retinoid Component selected from the group consisting of active agents, retinoids retinoids, precursors of active agents and mixtures thereof for preparing a Pharmaceutical composition for use in a method for providing a desired therapeutic effect, as is R nodulocystic acne, to a human or animal with a Gastrointestinal TractOr has a certain body weight, wherein Said method comprises: orally administering to a human or animal a therapeutically effective amount of said Component a retinoidWhere the administration is effective to provide a desired therapeutic effect, and to provide a more consistent bioavailability of retinoid Component to human or animal in the presence and Absence of food in the Gastrointestinal Tract of human or animal with respect to Employment d The Place of the retinoid Component and Isotretinoin orally Administration in a step of the same.Preferably, administered systemically to provide a maximum Blood concentration of retinoid Active Agent in human or animal more than 30 ng / ml, providing a minor side effect or, at least, a SIDE EFFECT reduced with respect to the use of A retinoid Agent reference.