Modulation methods of production of a compound containing sulfur by a microorganism and production of methionine, transgenic expression cassette, vector, host cell and transgenic.

摘要

"Modulation methods of production of a compound containing sulfur by a microorganism and production of methionine, transgenic expression cassette, vector, host cell and transgenic.Nucleic acid molecules, nucleic acid molecules, called Mr.That encode new proteins Mr. of Corynebacterium glutamicum are described which are involved in the biosynthesis of a chemical compound thin, for example in the biossintese methionine.The invention also provides nucleic acid molecules of anti sense.Vectors and transgenic expression cassettes containing nucleic acid molecules, and host cells for Mr. within which the vectors or expression cassettes have been introduced.The invention additionally provides methods for the production of methionine from microorganisms, e.g. C.Glutamicum, which involves the culture of recombinant microorganisms that superexpressam or subexpressam at least one molecule Mr. of the invention under conditions such that methionine is produced.Also are provided methods of producing a fine chemical, e.g., methionine.It involves the culture of recombinant microorganisms possessing genes deleted or mutados Mr. selected under conditions such that the fine chemical, for example, methionine, is produced.