首页> 外国专利> Combination of a) n- {5- 4- (4-methyl-piperazine-methyl) -benzoylamido -2-methyl-phenyl} -4- (3-pyridyl) -2-pyrimidine-amine and b) a deacetylase inhibitor of histone for the treatment of leukemia

Combination of a) n- {5- 4- (4-methyl-piperazine-methyl) -benzoylamido -2-methyl-phenyl} -4- (3-pyridyl) -2-pyrimidine-amine and b) a deacetylase inhibitor of histone for the treatment of leukemia

机译:a)n- {5- [4- [4-(4-甲基-哌嗪-甲基)-苯甲酰胺基] -2-甲基-苯基} -4-(3-吡啶基)-2-嘧啶-胺与b)脱乙酰酶的组合组蛋白抑制剂治疗白血病

摘要

"COMBINATION OF a) N- {5- [4- (4-METHYPYPERAZINO-METHYL) -BENZOYLAMIDOI-2-METHYL PHENYL) -4- (3-PYRIDYL) -2-PYRIMIDINE-AMINE; HISTON FOR THE TREATMENT OF LEUKEMIA ". The invention pertains to a combination of a histone deacetylase inhibitor and N- {5- [4- (4-methyl-piperazine-methyl) -benzoylamido] -2-methylphenyl} -4- (3-pyridyl) -2-pyrimidine or a pharmaceutically acceptable salt thereof for simultaneous, separate or sequential use for the treatment of leukemia and especially N-15- [4- (4-methyl-piperazine-methyl) -benzoylaminol-2-methylphenyl) -4- (3) -pyridyl) -2-pyrimidine.
机译:“ a)N- {5- [4-(4-甲基高叠氮基甲基)-苯甲酰氨基-2-甲基苯基)-4-(3-吡啶基)-2-嘧啶-氨基的组合;希斯顿用于白血病的治疗“ 。本发明涉及组蛋白脱乙酰基酶抑制剂和N- {5- [4-(4-甲基-哌嗪-甲基)-苯甲酰胺基] -2-甲基苯基} -4-(3-吡啶基)-2-嘧啶的组合或用于同时,分别或依次用于治疗白血病,尤其是N-15- [4-(4-甲基-哌嗪-甲基)-苯甲酰基氨基-2-甲基苯基)-4-(3)-吡啶基的药学上可接受的盐)-2-嘧啶。

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