Azabiciclicos compounds derived from N - arilsulfonilpiperidinas; inhibitors of the deposition of Amyloid beta protein; Pharmaceutical Composition and its use for the treatment of Alzheimer's disease and illnessNeurodegenerative disease.

摘要

In an embodiment, this invention discloses novel gamma secretase inhibitors of Formulae I: wherein the various moieties are described herein. Also disclosed is a method of treating Alzheimer's disease using a compound of Formula I or a composition comprising the compound of Formula I.