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Transformational system before comparing the area of filamentous fungal hosts: In the chrysosporium

机译:比较丝状真菌宿主面积之前的转化系统:在金孢菌属中

摘要

A novel transformation system in the field of filamentous fungal hosts for expressing and secreting heterologous proteins or polypeptides is described. The invention also covers a process for producing large amounts of polypeptide or protein in an economical manner. The system comprises a transformed or transfected fungal strain of the genus Chrysosporium, more particularly of Chrysosporium lucknowense and mutants or derivatives thereof. It also covers transformants containing Chrysosporium coding sequences, as well expression-regulating sequences of Chrysosporium genes. Also provided are novel fungal enzymes and their encoding sequences and expression-regulating sequences.
机译:描述了丝状真菌宿主领域中用于表达和分泌异源蛋白质或多肽的新型转化系统。本发明还涵盖了以经济的方式生产大量多肽或蛋白质的方法。该系统包括金孢菌属的转化的或转染的真菌菌株,更特别地是勒克氏梭菌的真菌菌株及其突变体或衍生物。它还涵盖了包含金孢菌编码序列以及金孢菌基因表达调节序列的转化体。还提供了新颖的真菌酶及其编码序列和表达调节序列。

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