COMBINED APPLICATION OF ANTI-TUMOR DERIVATIVE OF INDOLOPYRROLOCARBAZOLE AND ANOTHER ANTITUMOR AGENT

摘要

The present invention relates to a combined preparation for simultaneous, separate or sequential administration in the treatment of cancer, containing two separate preparations: a preparation containing at least one compound of general formula I in combination with a pharmaceutically acceptable carrier or diluent, where each of the substituents R and R is independently of each other is a hydrogen atom, lower alkyl or others. and G is pentosyl or others, X and X, each independently of one another, is a hydrogen atom, atoms m halogen or other, or its pharmaceutically acceptable sa and the drug in combination with a pharmaceutically acceptable carrier or diluent, such as antitumor alkylating agents, antitumor antimetabolites, antitumor antibiotics or antitumor agents of plant origin (a preparation containing at least one compound of general formula I or its pharmaceutically acceptable salt, can be combined with two or more other anticancer agents), and a method of treating cancer, which involves the introduction of these drugs in combination.International This was published with the international search report.