USE OF VITAMIN D-DERIVATIVES FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS USEFUL IN THE TREATMENT OF OSTEOPOROSIS AND RELATED BONE DISORDERS, AS WELL AS NOVEL VITAMIN D3-DERIVATIVES

摘要

Compounds of the formula I wherein X represents hydrogen or hydroxy; Y represents oxygen or sulphur or oxidized sulphur selected from the groups S(O) and S(OSUB2/SUB); RSUP1 /SUPand RSUP2/SUP, which may be the same or different, represent hydrogen or a residue after removal of 1 hydrogen atom from a straight, branched or cyclic, saturated or unsaturated, CSUB1/SUB-CSUB6/SUB-hydrocarbon; or RSUP1 /SUPand RSUP2/SUP, together with the carbon atom to which they are attached (marked with an asterisk in formula I), bearing the group X, form a CSUB3/SUB-CSUB8 /SUBcarbocyclic ring; Q represents a diradical residue after removal of 2 hydrogen atoms from a straight, branched or cyclic, saturated or unsaturated CSUB1/SUB-CSUB8/SUB-hydrocarbon; and RSUP3 /SUPrepresents hydrogen or a residue after removal of 1 hydrogen atom from a straight, branched or cyclic, saturated or unsaturated CSUB1/SUB-CSUB6/SUB-hydrocarbon; may be used for the preparation of a medicament for the treatment and/or prophylaxis of osteoporosis and related bone disorders.