首页> 外国专利> USE OF N-PHENYL-2-PYRIMIDINEAMINE DERIVATIVES FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS SUITABLE FOR TREATING MAST CELL-BASED DISEASES LIKE ALLERGIC DISORDERS

USE OF N-PHENYL-2-PYRIMIDINEAMINE DERIVATIVES FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS SUITABLE FOR TREATING MAST CELL-BASED DISEASES LIKE ALLERGIC DISORDERS

机译:N-苯基-2-嘧啶亚胺衍生物在制备药物组合物中的应用,该组合物适合治疗基于变态反应的肥大细胞疾病

摘要

The present invention relates to the use of the N-phenyl-2-pyrimidineamine derivatives of formula (I) in free form or in a pharmaceutically acceptable salt form for allergic rhinitis, allergic dermatitis, drug allergy, food allergy, angioedema, urticaria, sudden infant death syndrome, bronchopulmonary aspergillosis for the manufacture of a medicament for the treatment of multiple sclerosis or mastocytosis. Preferred meanings of the substituents are R1, R3, R5, R6, R8 are hydrogen, R2 is pyridyl, R4 is alkyl, R7 is substituted benzoylamino. SHE
机译:本发明涉及游离形式或药学上可接受的盐形式的式(I)的N-苯基-2-嘧啶胺衍生物在过敏性鼻炎,过敏性皮炎,药物过敏,食物过敏,血管性水肿,荨麻疹,突然发作中的用途婴儿死亡综合症,支气管肺曲霉病,用于制造治疗多发性硬化或肥大细胞增多症的药物。取代基的优选含义是R 1,R 3,R 5,R 6,R 8是氢,R 2是吡啶基,R 4是烷基,R 7是取代的苯甲酰基氨基。她

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