首页> 外国专利> PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED DIPHENYL INDANONE, INDANE AND INDOLE COMPOUNDS AND ANALOGUES THEREOF USEFUL FOR THE TREATMENT OR PREVENTION OF DISEASES CHARACTERIZED BY ABNORNAL CELL PROLIFERATION AND SOME SUCH NOVEL COMPOUNDS

PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED DIPHENYL INDANONE, INDANE AND INDOLE COMPOUNDS AND ANALOGUES THEREOF USEFUL FOR THE TREATMENT OR PREVENTION OF DISEASES CHARACTERIZED BY ABNORNAL CELL PROLIFERATION AND SOME SUCH NOVEL COMPOUNDS

机译：包含取代的二苯茚基茚满，茚满和吲哚化合物的药物组合物及其类似物，这些药物可用于治疗或预防异常细胞增生和某些此类新化合物的疾病

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摘要

The present invention provides substituted 3,3-diphenyl indanone, indane and indole compounds, as well as analogues thereof, which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inhibit mammalian cell proliferation in situ as a therapeutic approach towards the treatment or prevention of diseases characterized by abnormal cell proliferation, such as cancer.

机译：本发明提供了取代的3，3-二苯基茚满酮，茚满和吲哚化合物及其类似物，它们是哺乳动物细胞增殖的特异性，有效和安全的抑制剂。所述化合物可用于原位抑制哺乳动物细胞增殖，作为治疗或预防以异常细胞增殖为特征的疾病如癌症的治疗方法。

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公开/公告号IL136227A

专利类型
公开/公告日2005-09-25

原文格式PDF
申请/专利权人 PRESIDENT AND FELLOWS OF HARVARD COLLEGE;NUCHEM PHARMACEUTICALS INC.;THE CHILDRENS MEDICAL CENTER CORPORTION;
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申请/专利号IL19980136227
发明设计人
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申请日1998-11-20
分类号A61K31/015;A61K31/03;A61K31/165;A61K31/235;A61K31/275;A61K31/335;A61K31/40;A61P9/10;A61P17/00;A61P29/00;A61P35/00;C07C22/04;C07C33/34;C07C35/32;C07C39/12;C07C43/188;C07C47/00;C07C49/67;C07C62/00;C07C63/00;C07C65/00;C07C69/74;C07C205/00;C07C211/00;C07C215/00;C07C217/00;C07C229/00;C07C233/00;C07C239/08;C07C251/44;C07C255/40;C07C259/10;C07C313/18;C07C321/00;C07C323/00;C07C325/00;C07C327/00;C07D209/10;C07D209/30;C07D303/48;C07D317/14;
国家 IL
入库时间 2022-08-21 22:17:48

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