RING-SUBSTITUTED 8 AMINOQUINOLINE ANALOGUES AS ANTIMALARIAL AGENTS

摘要

The present invention relates to ring-substituted 8-aminoquinoline analogues useful as antimalarial agents.The present invention also relates to a process for preparation of ring-substituted 8-aminoquinoline analogues useful as antimalarial agents. The present invention particularly relates to synthesis of 2-alkyl-4.5-disubstitited-6-methoxyprimaquine analogues having the formula 1. which are expected to offer an improved means for the chemotherapy of malaria