首页> 外国专利> A SYNERGISTIC VACCINE FROMULATION POTENTIATED BY THE COMBINATION OF DNA AND AN ANTIGEN

A SYNERGISTIC VACCINE FROMULATION POTENTIATED BY THE COMBINATION OF DNA AND AN ANTIGEN

机译:DNA和抗原结合后产生协同疫苗的潜力

摘要

Synergistic formulation of vaccine antigens, containing as main components: a-) one or several DNA expressing one or several proteins in the immunized individuals and b-) a viral antigen, in appropriate proportions. The novelty of the invention is given by the enhancing effect of at least one component on the immune response generated against the other one. Development of new formulations, minimizing the number of components that enhance and diversify the spectrum of immune response against different pathogenic entities and generating combined vaccines against pathogens. These formulations can be applied in the pharmaceutical industry for preventive and-or therapeutic use in human.
机译:疫苗抗原的协同制剂,其包含以下主要成分:a-)适当比例的一种或几种在免疫个体中表达一种或几种蛋白质的DNA和b-)病毒抗原。通过至少一种组分对针对另一种组分产生的免疫应答的增强作用来给出本发明的新颖性。开发新配方,最大程度减少增强和多样化针对不同病原体的免疫反应范围的成分数量,并生成针对病原体的组合疫苗。这些制剂可以在制药工业中用于人类的预防和/或治疗用途。

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