1,2,4-setnar 1,2,3,4-tetrahýdró-og 1,2 díhýdró-kínólín og 1,2,3,4-tetrahýdró-kínoxalín afleiður semCETP hindrar til meðferðar á fituhrörnun og offitu

摘要

Quinoline and quinoxaline compounds of formula I and III wherein the subtituent are as defined in claims 1 and 15, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.