a new method of synthesis of the derivatives of the acid (2s, 3as, 7as) - 1 - (s) - alanyl), - 1h indole - 2 - acid and application to the synthesis of perindopril

摘要

a new method of synthesis of the derivatives of the acid (2s, 3as, 7as) - 1 - [(s) - alanyl), - 1h indole - 2 - acid and application to the synthesis of perindopril industrial synthesis of compounds of formula (i): in which r1 is a hydrogen atom or an alkyl group or benzyl; r2 is a protecting group and the amino group.application to the synthesis of perindopril and pharmaceutically acceptable salts of these.