LIBRARIES OF CONFORMATIONALLY CONSTRAINED PEPTIDES, CHIRAL AZACROWNS, AND PEPTIDOMIMETICS AND METHODS OF MAKING THE SAME.

摘要

The present invention is directed to the making of library of conformationally constrained peptides and peptidomimetics including chiral azacrowns for use as conformational templates when complexed with metals for the production of conformationally constrained bioactive peptides for use in elucidation of the binding sites and functional groups on the receptor/peptide ternary complex.