首页> 外国专利> CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEUROPATHIC PAIN AND CLUSTER AND MIGRAINE HEADACHE-ASSOCIATED PAIN.

CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEUROPATHIC PAIN AND CLUSTER AND MIGRAINE HEADACHE-ASSOCIATED PAIN.

机译:氨基甲酸酯化合物,用于预防或治疗神经病性疼痛以及与头痛和头疼的头痛相关联的疼痛。

摘要

This invention is directed to a method for preventing or treating neuropathic pain and cluster and migraine headache-associated pain comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I): Formula (I) wherein phenyl is substituted at X with one to five halogen atoms independently selected from the group consisting of fluorine, chlorine, bromine and iodine; and; R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of hydrogen, halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
机译:本发明涉及预防或治疗神经性疼痛以及与丛集性和偏头痛相关的疼痛的方法,该方法包括向有需要的受试者施用治疗有效量的式(I)的化合物:式(I)的化合物,其中苯基被取代在X处具有1-5个独立地选自氟,氯,溴和碘的卤素原子;和; R1,R2,R3和R4独立地选自氢和C1-C4烷基;其中C1-C4烷基任选地被苯基取代(其中苯基任选地被独立地选自氢,卤素,C1-C4烷基,C1-C4烷氧基,氨基,硝基和氰基的取代基取代)。

著录项

  • 公开/公告号MXPA04000554A

    专利类型

  • 公开/公告日2005-02-17

    原文格式PDF

  • 申请/专利权人 JOHNSON & JOHNSON;

    申请/专利号MX2004PA00554

  • 发明设计人 CARLOS R. PLATA-SALAMAN;

    申请日2002-07-11

  • 分类号A61K31/27;A61P25/06;

  • 国家 MX

  • 入库时间 2022-08-21 22:17:28

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