首页> 外国专利> CYCLIC NITROMETHYL ACETIC ACID DERIVATIVES.

CYCLIC NITROMETHYL ACETIC ACID DERIVATIVES.

机译:环亚甲基乙酸衍生物。

摘要

The invention provides salts of formula (I) wherein X is a basic counterion selected from a group I or group II metal and a primary, secondary or tertiary amine; n is 0, 1 or 2; and Rl, Rla, R2, R2a, R3, R3a, R4 and R4a are independently selected from H and C1-C6 alkyl, or R1 and R2 or R2 and R3 are taken together to form a C3-C7 cycloalkyl ring, which is optionally substituted with one or two substituents selected from C1-C6 alkyl, which are useful as intermediates in the preparation of cyclic and bicyclic amino acids. Processes for the preparation of the final products and for the conversion of the compounds of formula ( OE) to amino acids are included.
机译:本发明提供了式(I)的盐,其中X是选自I或II族金属和伯,仲或叔胺的碱性抗衡离子; n为0、1或2; R1,R1a,R2,R2a,R3,R3a,R4和R4a独立地选自H和C1-C6烷基,或R1和R2或R2和R3一起形成C3-C7环烷基环,其任选地是取代有一个或两个选自C 1 -C 6烷基的取代基,它们用作制备环状和双环氨基酸的中间体。包括制备最终产物和将式(OE)的化合物转化为氨基酸的方法。

著录项

  • 公开/公告号MXPA05003520A

    专利类型

  • 公开/公告日2005-06-03

    原文格式PDF

  • 申请/专利权人 PFIZER INC.;

    申请/专利号MX2005PA03520

  • 发明设计人 DERRICK ANDREW MICHAEL;

    申请日2003-09-22

  • 分类号C07C205/51;

  • 国家 MX

  • 入库时间 2022-08-21 22:17:16

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