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QUINOLINE AND QUINOXALINE COMPOUNDS AS PDGF-RECEPTOR AND/OR LCK TYROSINE KINASE INHIBITORS

机译:喹诺啉和喹喔啉化合物作为PDGF受体和/或LCK酪氨酸激酶抑制剂

摘要

This invention is directed to quinoline/quinoxaline compounds which inhibit platelet-derived growth factor or p56lck tyrosine kinase activity, to pharmaceutical compositions comprising these compounds, and to the use of these compounds for treating a patient suffering from or subject to disorders/conditions involving cellular differentiation, proliferation, extracellular matrix production or mediator release and/or T cell activation and proliferation.
机译:本发明涉及抑制血小板衍生的生长因子或p56lck酪氨酸激酶活性的喹啉/喹喔啉化合物,包含这些化合物的药物组合物,以及这些化合物在治疗患有或遭受涉及细胞疾病/病症的患者中的用途。分化,增殖,细胞外基质产生或介质释放和/或T细胞活化和增殖。

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