Active pyridine (3,4-c) pyrazol derivatives, used as quinase inhibitors, preparation process and drug synthesis containing this substance

摘要

It refers to a compound pyrrolidol [3,4-c] pyrazole, wherein R is h or methyl; R1 is hydroxyl, hydrocarbon or alcoxi c1-c 3 straight chain or branch; R2 is h or halogen; X is a compound with an isomeric component selected from methylene (- CH2 -).Hydrogen fluoride (- CHF -),A selective heteromorphic oxygen (- O -),There are others 1 - (1 - (1 -) (1 -, 1 - (1) - {5 - [(2R) - 2-methoxy-2-phenyl] - 1,4,5,6-tetrahydropyridine [3, 4 (c) pyrazole-3-il} - 4 - (4-isopropilpiperazin-1-il) benzene zamida; It also mentions a process for making these compounds and a drug synthesis. In addition, it refers to a method of treating cell proliferation disorder caused by a change and / or related protein activity.