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New enemies of acetylcholine m3 muscle receptor

机译:乙酰胆碱M3肌肉受体的新敌人

摘要

A compound of formula I, wherein X is C, O, y is C, n is 1-3, M is 1-3, P is 0-2, W is O, s, NH, u is NR3, O, link, R3 is h, C1-C8 tar, c3-c8, etc., q is 0-7, h is 0-2, G1-3, V is phenyl, endosulfan, endosulfan, furan, etc., R4 is h, oh, amino, Niels, fenit, pirik, etc., pirides, piride 0, Among other things, R5 is oxazolilo, imidazolino, oxadiazolilo; R1 is h, phenyl, furan, etc. The most popular compounds are n - [(3S) - 1 - [(3-hydroxyphenyl) methyl] - 1-methyl-3-pyridinediol} - N - [(5 - [(methyloxygen) carbides] - 2-furan} carbon] - L-thyroxine,N - [(4 - [(ethyl) carbonate] cyclohexane] - N - [(3S) - 1 - [(3-hydroxyphenyl) methyl] - 1-methyl-3-pyridinol} - L-thyroxine, etc. These compounds can be used to treat diseases transmitted by muscle receptors, such as pulmonary fibrosis, asthma, chronic bronchitis and so on.
机译:式I的化合物,其中X为C,O,y为C,n为1-3,M为1-3,P为0-2,W为O,s,NH,u为NR3,O, ,R3为h,C1-C8焦油,c3-c8等,q为0-7,h为0-2,G1-3,V为苯基,硫丹,硫丹,呋喃等,R4为h,哦,氨基,尼尔斯,菲尼特,皮里克等,pirides,piride 0,其中,R5是恶唑利洛,咪唑啉基,恶二唑基; R1为h,苯基,呋喃等。最受欢迎的化合物为n-[(3S)-1-[(3-羟苯基)甲基]-1-甲基-3-吡啶二醇}-N-[(5-[(甲基氧]碳化物]-2-呋喃}碳]-L-甲状腺素,N-[(4--((碳酸))环己烷]-N-[(3S)-1-[(3-羟苯基)甲基]-1 -甲基-3-吡啶醇} -L-甲状腺素等。这些化合物可用于治疗通过肌肉受体传播的疾病,例如肺纤维化,哮喘,慢性支气管炎等。

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