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LIGACAOCRUZADA STARCH WITH HIGH AMYLOSTIC CONTENT HAVING FUNCTIONAL GROUPS AS A MATRIX FOR THE SLOW LIBERATION OF PHARMACEUTICAL AGENTS
LIGACAOCRUZADA STARCH WITH HIGH AMYLOSTIC CONTENT HAVING FUNCTIONAL GROUPS AS A MATRIX FOR THE SLOW LIBERATION OF PHARMACEUTICAL AGENTS
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机译:具有功能基团的高支链淀粉含量的LIGACAOCRUZADA淀粉作为药物缓慢释放的矩阵
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摘要
The present invention is concerned with a solid slow release oral pharmaceutical dosage unit resistant to amylase which comprises a solid dosage unit made up of an admixture of a therapeutic dosage of an orally effective pharmaceutical product, an optional polysaccharide or polyol, and cross-linked high amylose starch, wherein the cross-linking of the high amylose starch has been carried out with a covalent or non-covalent cross-linking agent with from about 0.1 g to about 30 g of cross-linking agent per 100 g of high amylose starch.
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