ALKALINE SALTS N-(6-ALKYL-2,4-DIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINSULFONE)-N'-IZONICOTINOYLHYDRAZIDE WHICH CAN BE USED AS ANTIMICROBIAL AND IMMUNOTROPIC AGENTS, A METHOD FOR THE PREPARATION THEREOF, USE THEREOF AS IMMUNOMODULATOR AND PHARMACEUTICAL COMPOSITION BASED THEREON

摘要

Alkaline salts of N-(6-alkyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfone)-N'-isonicotinoylhydrazide of formula (I), where R is 1-4 carbon atoms alkyl and M is alkali metal, which can possess antimicrobial and immunothrope activities and can be used as immunomodulator are offered, as well as the method for producing these salts and pharmaceutical composition based on them. The offered salts may be used in treating chronic recurring diseases complicated with bacterial infections on the immunodeficiency background, also they may be used as antimicrobial means. (I)