OPHTHALMIC TETRACICLINE SOLUTION FOR THE TOPICAL TREATMENT OF DRY EYE SYNDROME

摘要

Ophthalmic preparation for topical application in the eye, the preparation comprising an aqueous solution containing (a) a tetracycline compound in an amount sufficient to treat an eye disease characterized by inflammation of the ocular surface; and (b) a balance of electrolytes selected from the group consisting of potassium, chloride, bicarbonate and sodium, in which said potassium is present in a concentration of about 22.0 to 43.0 mM / l, said bicarbonate is present in a concentration of about 29.0 to 50.0 mM / l, said sodium is present in a concentration of about 130.0 to 140.0 mM / l, and said chloride is present in a concentration of about 118.0 at 136.5 mM / l, or a therapeutically effective dilution or concentration of said solution.