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genetic markers for breast and ovarian cancer.

机译:乳腺癌和卵巢癌的遗传标记。

摘要

SPECIFIC USED BRCA1, PCR primers and probes hybridization PROCEDURES FOR NUCLEIC ACIDS BASED ON THE DIAGNOSIS OF BREAST CANCER SUSCEPTIBILITY hereditary. They are also used binding agents such as antibodies specific for the peptides encoded by BRCA1 DESCRIBED THE MUTANT to identify expression products DIAGNOSTICS mutational / rare alleles SAMPLES IN fluid or tissue derived from a patient. USED ​​compositions with a high binding affinity FOR PRODUCTS transcription or translation of BRCA1 Mutations Alleles DESCRIBED AND IN THERAPEUTIC INTERVENTIONS. These products include nucleic acids BY ANTI Nucleic acids described and binding agents such as antibodies, which are specific for such peptides.
机译:基于乳腺癌易感性遗传性诊断的特定使用的BRCA1,PCR引物和探针杂交程序。它们还用作结合剂,例如对BRCA1所描述的突变体编码的肽具有特异性的抗体,以鉴定来自患者的体液或组织中的表达产物DIAGNOSTICS突变/稀有等位基因样品。具有高结合亲和力的已使用组合物可用于描述和在治疗干预中描述的BRCA1突变等位基因产物的转录或翻译。这些产物包括所述的抗核酸核酸和对这类肽具有特异性的结合剂,例如抗体。

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