HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM

摘要

The present invention contemplateschromophore-containing polynucleotides havingat least two donor chromophores operativelylinked to the polynucleotide by linkerarms, such that the chromophores are positionedby linkage along the length of the polynucleotideat a donor-donor transfer distance,and at least one, fluorescing acceptorchromophore operatively linked to the polynucleotideby a linker arm, such that the fluorescingacceptor chromophore is positioned bylinkage at a donor-acceptor transfer distancefrom at least one of the donor chromophores,to form a photonic structure for collectingphotonic energy and transferring the energy toan acceptor chromophore, and methods usingthe photonic structures.