COMBINATIONS COMPRISING A PROTEIN TYROSNE KINASE RECEPTOR ANTAGONIST AND A CHEMOTHERAPEUTIC OR NATURALLY OCCURING, SEMI-SYNTHETIC OR SYNTHETIC THERAPEUTIC AGENT FOR THE TREATMENT OF DISEASES INVOLVING CELL PROLIFERATION, MIGRATION OR APOPTOSIS OF MYELOMA CELLS, OR ANGIOGENESIS

摘要

The present invention relates to a pharmaceutical combination for thetreatment of diseases which involves cell proliferation, migration orapoptosis of myeloma cells, or angiogenesis. The invention also relates to amethod for the treatment of said deseases, coomprising co-administration ofeffective amounts of specific active compounds and/or co-treatment withradiation therapy, in a ratio which provides an additive and synergisticeffect, and to the combined use of these specific compounds and/orradiotherapy for the manufacture of corresponding pharmaceutical combinationpreparations.