首页> 外国专利> Substituted 1, 3, 5-triazines and pyrimidines as ABCA-1 elevating compounds against coronary artery disease or atherosclerosis

Substituted 1, 3, 5-triazines and pyrimidines as ABCA-1 elevating compounds against coronary artery disease or atherosclerosis

机译:取代1,3,5-三嗪和嘧啶类药物作为ABCA-1增强化合物,可抵抗冠状动脉疾病或动脉粥样硬化

摘要

The present invention provides compounds that elevate cellular expression of the ABCA-1 gene, promoting cholesterol efflux from cells and increasing HDL levels in the plasma of a mammal, in particular humans. The compounds are useful for treating coronary artery disease.
机译:本发明提供了提高ABCA-1基因的细胞表达,促进胆固醇从细胞中流出并增加哺乳动物,特别是人血浆中HDL水平的化合物。该化合物可用于治疗冠状动脉疾病。

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