POLYMORPHISMS IN THE ESR1 GENE AND DIAGNOSIS OF AN ESTROGEN-SENSITIVE DISORDER

摘要

The method of the invention is useful for diagnosing an increased or decreased risk of an estrogen-sensitive disease in an individual. The evaluation of the risk of disease comprises determining whether the ERalpha gene or 3'UTR an individual comprises one or more of the polymorphisms defined herein as ISOE1, ISOE2, ISOE3, ERNE1, ERNE2, ISOC1, 2a1, 2a2, 2a3, 2a4, 2a5, 8B1, 8B2, 8C, 8E, 8H or 8I.