首页> 外国专利> IMPLANTABLE OR INSERTABLE MEDICAL DEVICES CONTAINING MISCIBLE POLYMER BLENDS FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT

IMPLANTABLE OR INSERTABLE MEDICAL DEVICES CONTAINING MISCIBLE POLYMER BLENDS FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT

机译:含可混溶聚合物掺混物的可植入或不可植入医疗设备,用于控制治疗剂的输送

摘要

A therapeutic-agent release region is described, which comprises: (i) a first phase comprising a plurality of miscible polymers that are miscible with one another and (ii) a second phase comprising an additional polymer, which can be immiscible with any or all of the plurality of miscible polymers or a blend of the miscible polymers. Also described is a therapeutic-agent-releasing medical device, which comprises: (a) an implantable or insertable medical device substrate; (b) the above release region, disposed over at least a portion of the implantable or insertable medical device substrate, and (c) a therapeutic agent. The release region regulates the rate of release of the therapeutic agent from the medical device upon implantation or insertion of the device into a patient. Also described are methods for making an implantable or insertable medical device, for administering a therapeutic agent to a patient, and for modulating the release rate of a therapeutic agent.
机译:描述了一种治疗剂释放区域,其包括:(i)包含多种彼此可混溶的可混溶聚合物的第一相,和(ii)包含可与任何或全部不混溶的另外的聚合物的第二相。多种可混溶的聚合物中的一种或多种可混溶的聚合物的混合物。还描述了一种释放治疗剂的医疗器械,其包括:(a)可植入或可插入的医疗器械基底; (b)上述释放区域,其布置在可植入或可插入医疗装置基底的至少一部分上,和(c)治疗剂。释放区域在将装置植入或插入患者体内时调节治疗剂从医疗装置的释放速率。还描述了制造可植入或可插入医疗装置,向患者施用治疗剂以及调节治疗剂释放速率的方法。

著录项

  • 公开/公告号WO2004080397A3

    专利类型

  • 公开/公告日2004-12-02

    原文格式PDF

  • 申请/专利权人 SCIMED LIFE SYSTEMS INC;SCHWARZ MARIENE C.;

    申请/专利号WO2004US06853

  • 发明设计人 SCHWARZ MARIENE C.;

    申请日2004-03-05

  • 分类号A61K47/32;A61L31/00;

  • 国家 WO

  • 入库时间 2022-08-21 22:12:40

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