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A CONFOCAL MICROSCOPE SYSTEM FOR REAL-TIME SIMULTANEOUS TEMPORAL MEASUREMENTS OF METACHRONAL WAVE PERIOD AND CILIARY BEAT FREQUENCY
A CONFOCAL MICROSCOPE SYSTEM FOR REAL-TIME SIMULTANEOUS TEMPORAL MEASUREMENTS OF METACHRONAL WAVE PERIOD AND CILIARY BEAT FREQUENCY
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机译:共焦显微镜系统,用于实时同步测量拍子波周期和睫状肌节拍频率
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摘要
The present invention relates to a method and system that enables continuous real-time analysis of both ciliary beat frequency and metachronal wave frequency from a single spot (107) in excised native ciliated epithelial tissues as well as in primary and subsequent epithelial cultures. Such method and system utilizes the concept of time-scale wavelet analysis and Hilbert Transformation (112) for backscattered light derived from a confocal (conjugate) spot on the moving cilia. This light contains inherent high and low frequency components corresponding to CBF and MWF.
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