FORMULATION OF THE TOTAL ANHYDRIDES OF CANTHARIDIN FOR THE TREATMENT AND PREVENTION OF SEVERE ACUTE RESPIRATORY SYNDROME INFECTIONS AND THE PREPARATION THEREOF

摘要

A formulation of the total anhydrides of cantharidin for the treatment and prevention of Severe Acute Respiratory Syndrome, which is characterized in containing the total anhydrides of cantharidin as an effective ingredient as well as pharmaceutical acceptable essential oil or synthetic perfume as a solvent. Moreover the total anhydrides of cantharidin will be present in amount within the range of from 0.05 to 7 %. The preparation comprises the following steps: (1) add a measured amount of the total anhydides of cantharidin into the essential oil or the synthetic perfume, and stir to make the total anhydrides of cantharidin dissolved into essential oil at 40-160 °C and under normal pressure, the formulation of total anhydrides of cantharidin-essential oil is then obtained; (2) mix a measured amount of the formulation of total anhydrides of cantharidin-essential oil or synthetic perfume and pharmaceutical carrier or excipient, stir uniformly, and the desired pharmaceutical composition is obtained.