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SELECTIVE INHIBITORS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2
SELECTIVE INHIBITORS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2
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机译:前列腺素内酯过氧化物合成酶2的选择性抑制剂
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摘要
The present invention provides a compound of the formulawherein when X is S; R is selected from the group consisting of CH3, CH2CH3, CH2Ph, (CH2)2Ph, (CH2)2CH3, (CH2)3CH3, (CH2)4CH3, CH2)5CH3, (CH2)6CH3, (CH2)2O(CH2)3CH3, CH2HC=CH(CH2)3CH3, CH2C=C(CH2)3CH3, CH2C=C(CH2)2CH3, CH2C=CCH2CH3, CH2C=CCH3, CH2C=CH, CH2C=C(CH2)4CH3, CH2C=C(CH2)5CH3, CH2C=C(CH2)6CH3, (CH2)2C=C(CH2)2CH3, CH(Ch3)C=C(CH2)3CH3, (CH2)6I, (CH2)6Br, (CH2)5Br, (CH2)5COOH and (CH2)5OCOCH3, and R' is selected from the group consisting of CH3, CF
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