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PROCESS FOR ALKYLATING HINDERED SULFONAMIDES USEFUL IN THE PRODUCTION OF MATRIX METALLOPROTENASE INHIBITORS
PROCESS FOR ALKYLATING HINDERED SULFONAMIDES USEFUL IN THE PRODUCTION OF MATRIX METALLOPROTENASE INHIBITORS
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机译:用于生产基质金属蛋白酶抑制剂的碱化后亚磺酰胺的工艺
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摘要
The present invention relates to a process for the preparation of compounds of formula (b), in which a compound of formula V is reacted with a compound of formula VI. The resulting compound of formula IV is reduced to a compound of formula III which is hydrolysed to a compound of formula (b). Alternatively, a compound of formula IV is hydrolysed to a compound of formula (a) which reduced to a compound of formula (b). Compounds of formula IV are novel. In the formulae the variables are as defined in the claims. CHEM
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